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What other drugs will affect Xanax?

Do not take ketoconazole (Nizoral) or itraconazole (Sporanox) during treatment with Xanax without first talking to your doctor.
Xanax may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.
Antacids may decrease the effects of Xanax. Separate doses of an antacid and Xanax by several hours whenever possible.
Drugs other than those listed here may also interact with Xanax. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.


 

Where can I get more information?

Your pharmacist has additional information about Xanax written for health professionals that you may read.